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BPC-157 Peptide – 5mg/10mg/20mg

Q: What is BPC-157 peptide?

BPC-157 (Body Protection Compound-157) is a synthetic pentadecapeptide composed of 15 amino acids, derived from a protein found in human gastric juice. It has been extensively studied in rat models for its effects on wound healing, tissue repair, angiogenesis, cytoprotection, and neurological biochemistry under controlled experimental conditions.

Q: What are the main mechanisms of action for BPC-157?

BPC-157 works through angiogenesis and vasculogenesis, anti-inflammatory effects, cell proliferation and migration, neuroprotective effects, and gastroprotective effects on the GI tract.

Q: What benefits has research suggested for BPC-157?

Studies in rodents and cultured cells suggest BPC-157 may promote healing in tendons, joints, nerves, intestinal tract, stomach, and skin. More research is needed to determine the benefits in humans.

Q: How should BPC-157 be stored?

Lyophilized BPC-157 should be stored at -20°C. Aliquot reconstituted peptide into several discrete vials to avoid repeated freezing and thawing. Reconstituted protein can be stored at 4°C.

Q: Is BPC-157 approved for human use?

No, BPC-157 is sold for research purposes only. It is not intended for weight loss, human consumption, or veterinary use.

Q: What future research is needed for BPC-157?

Future research should focus on conducting large-scale randomized controlled trials, elucidating precise molecular mechanisms, assessing long-term safety, and exploring combination therapies.

Q: What does BPC-157 do in research?

In preclinical studies, BPC-157 has been shown to enhance granulation, angiogenesis, and collagen deposition in wound models. It also modulates regional serotonin synthesis in rat brains, protects against gastric lesions, and demonstrates rapid systemic distribution with a short elimination half-life after intramuscular administration in rats.

Q: What is the best peptide for healing in research?

BPC-157 is one of the most extensively studied peptides for healing in preclinical research, with documented effects on tendons, ligaments, muscles, skin, and the gastrointestinal tract. Other commonly studied healing peptides include TB-500 (Thymosin Beta-4) for muscle and cardiac repair and GHK-Cu for skin regeneration and collagen remodeling.

Q: What sizes does BPC-157 come in?

NuScience Peptides offers BPC-157 in 5mg, 10mg, and 20mg lyophilized vials, as well as oral BPC-157 capsules (500mcg, 60 count). All formats are 99% pure, independently tested, and supplied with complete Certificates of Analysis.

Q: Where is BPC-157 peptide for sale?

BPC-157 peptide is for sale at NuScience Peptides in 5mg, 10mg, and 20mg research-grade vials. All products are independently tested via HPLC and mass spectrometry, with same-day shipping on in-stock orders before 12:00 PM EST and free shipping over $200.

Price range: $34.99 through $109.00

5mg/10mg/20mg per vial

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Properties

Molecular Formula	C₆₂H₉₈N₁₆O₂₂
Molecular Weight	1419.5
Monoisotopic Mass	1417.70415882
Polar Area	574
Complexity	3040
XLogP	-9
Heavy Atom Count	100
Hydrogen Bond Donor Count	16
Hydrogen Bond Acceptor Count	24
Rotatable Bond Count	39
Physical Appearance	Fine White Lyophilized Powder
Stability	Lyophilized protein is to be stored at -20°C. It is recommended to aliquot the reconstituted (dissolved) protein into several discrete vials in order to avoid repeated freezing and thawing. Reconstituted protein can be stored at 4°C
PubChem LCSS	BPC – 157 Laboratory Chemical Safety Summary

Identifiers

CID	9941957
CAS	137525-51-0
InChI	InChI=1S/C62H98N16O22/c1-31(2)25-37(55(92)74-50(32(3)4)62(99)100)71-46(81)29-65-51(88)33(5)67-53(90)38(26-48(84)85)73-54(91)39(27-49(86)87)72-52(89)34(6)68-57(94)41-15-10-21-75(41)58(95)35(13-7-8-20-63)70-45(80)30-66-56(93)40-14-9-22-76(40)60(97)43-17-12-24-78(43)61(98)42-16-11-23-77(42)59(96)36(18-19-47(82)83)69-44(79)28-64/h31-43, 50H, 7-30, 63-64H2, 1-6H3, (H, 65, 88)(H, 66, 93)(H, 67, 90)(H, 68, 94)(H, 69, 79)(H, 70, 80)(H, 71, 81)(H, 72, 89)(H, 73, 91)(H, 74, 92)(H, 82, 83)(H, 84, 85)(H, 86, 87)(H, 99, 100)/t33-, 34-, 35-, 36-, 37-, 38-, 39-, 40-, 41-, 42-, 43-, 50-/m0/s1
InChIKey	HEEWEZGQMLZMFE-RKGINYAYSA-N
Isomeric SMILES	C[C@@H](C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)O)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCCN)NC(=O)CNC(=O)[C@@H]2CCCN2C(=O)[C@@H]3CCCN3C(=O)[C@@H]4CCCN4C(=O)[C@H](CCC(=O)O)NC(=O)CN
Canonical SMILES	CC(C)CC(C(=O)NC(C(C)C)C(=O)O)NC(=O)CNC(=O)C(C)NC(=O)C(CC(=O)O)NC(=O)C(CC(=O)O)NC(=O)C(C)NC(=O)C1CCCN1C(=O)C(CCCCN)NC(=O)CNC(=O)C2CCCN2C(=O)C3CCCN3C(=O)C4CCCN4C(=O)C(CCC(=O)O)NC(=O)CN
IUPAC Name	(4S)-4-[(2-aminoacetyl)amino]-5-[(2S)-2-[(2S)-2-[(2S)-2-[[2-[[(2S)-6-amino-1-[(2S)-2-[[(2S)-1-[[(2S)-3-carboxy-1-[[(2S)-3-carboxy-1-[[(2S)-1-[[2-[[(2S)-1-[[(1S)-1-carboxy-2-methylpropyl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxohexan-2-yl]amino]-2-oxoethyl]carbamoyl]pyrrolidine-1-carbonyl]pyrrolidine-1-carbonyl]pyrrolidin-1-yl]-5-oxopentanoic acid

Description

BPC-157 Peptide: Advancing Research in Healing and Recovery

This product is not intended for weight loss, human consumption, or veterinary use. It is sold for research purposes only. Please handle with care and follow all safety guidelines for the specific chemicals involved.

What Is BPC-157 Peptide?

Body-protective compound 157 (BPC157) is a stable gastric pentadecapeptide extensively studied in experimental rat models for its biological effects under controlled conditions. It is not an approved therapeutic in humans, but preclinical research shows diverse influences on tissue healing, neurological biochemistry, and systemic pharmacokinetics in rodents.

BPC-157 Peptide in Wound Healing and Tissue Repair Research

In wound healing and tissue repair paradigms, BPC157 has been shown to enhance granulation, angiogenesis, and collagen deposition in rats. In models including skin incisional wounds, colon-colon anastomoses, and implanted synthetic sponges, rats treated with BPC157 exhibited significantly better healing outcomes compared with controls across different administration routes (e.g., intragastric and local application). This suggests robust promotion of connective tissue repair and vascularization in injured tissues. (PubMed)

BPC-157 5mg to 20mg: Pharmacokinetics in Rat Models

Pharmacokinetic studies in rats reveal rapid systemic distribution after intramuscular administration, with a relatively short elimination half-life (< 30 min) and primary excretion via urine and bile. BPC157 is metabolized into smaller peptide fragments, eventually entering normal amino acid metabolism pathways. These profiles help define exposure and clearance in rodent models, which are crucial for interpreting dose–response and safety in experimental conditions. (PubMed)

BPC-157 Peptide and Neurological Pathway Research

Beyond wound repair, BPC157 affects neurological and biochemical pathways in rat studies. For example, acute and repeated dosing altered regional serotonin synthesis in rat brains, with significant modulatory effects on areas such as the hippocampus and hypothalamus, indicating central nervous system influences extending beyond peripheral tissue healing. (PubMed)

BPC-157 for Sale: Research Summary and Safety Profile

Overall, experimental use of BPC157 in rats spans multiple systems, consistently demonstrating pro-healing and modulatory actions under controlled experimental conditions. These findings form the basis for ongoing interest in translational research, although clinical validation in humans remains limited.

Buy BPC-157 from NuScience Peptides to support your tissue repair and cytoprotection research. For synergistic studies, explore the BPC-157/TB-500 Blend and the GLOW Blend (GHK-Cu, BPC-157, TB-500). BPC-157 is also available in oral BPC-157 Capsule format. Use our Peptide Calculator to determine reconstitution volumes.

References (APA):
He, F., Guo, Z., Zhou, L., Li, X., Zhang, L., Zhang, Z., … & Li, L. (2022). Pharmacokinetics, distribution, metabolism, and excretion of body-protective compound 157, a potential drug for treating various wounds, in rats and dogs. PubMed. (PubMed)

Sikiric, P., Seiwerth, S., Grabarevic, Z., Petek, M., Rucman, R., Turkovic, B., … & Rotkvić, I. (1997). BPC 157’s effect on healing: Organoprotective actions in experimental rat models. Journal of Physiology-Paris. (PubMed)

Tao, R., & Li, J. (2004). Effects of pentadecapeptide BPC157 on regional serotonin synthesis in the rat brain: Alpha-methyl-L-tryptophan autoradiographic measurements. PubMed. (PubMed)

ALL LITERATURE, INFORMATION, AND DATA, PROVIDED ON THIS WEBSITE ARE FOR INFORMATIONAL AND EDUCATIONAL PURPOSES ONLY.

Accurate research is our number one priority.

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Frequently Asked Questions

Everything you need to know about BPC-157

1
What is BPC-157 peptide?

BPC-157 (Body Protection Compound-157) is a synthetic pentadecapeptide composed of 15 amino acids, derived from a protein found in human gastric juice. It has been extensively studied in rat models for its effects on wound healing, tissue repair, angiogenesis, cytoprotection, and neurological biochemistry under controlled experimental conditions.

2
What are the main mechanisms of action for BPC-157?