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Ipamorelin – 5mg

Original price was: $49.99.Current price is: $37.99.

5 mg per vial

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Properties

Molecular Formula

C38H49N9O5

Molecular Weight 711.9
Monoisotopic Mass 711.38566570
Polar Area 240
Complexity1200
XLogP 1.8
Heavy Atom Count 52
Hydrogen Bond Donor Count 8
Hydrogen Bond Acceptor Count 8
Rotatable Bond Count 19
Physical Appearance Fine White Lyophilized Powder
StabilityLyophilized protein is to be stored at -20°C. It is recommended to aliquot the reconstituted (dissolved) protein into several discrete vials in order to avoid repeated freezing and thawing. Reconstituted protein can be stored at 4°C
PubChem LCSS

Ipamorelin Laboratory Chemical Safety Summary

Identifiers

CID9831659
CAS170851-70-4
InChIInChI=1S/C38H49N9O5/c1-38(2, 41)37(52)47-32(21-28-22-42-23-43-28)36(51)46-31(20-25-15-16-26-12-6-7-13-27(26)18-25)35(50)45-30(19-24-10-4-3-5-11-24)34(49)44-29(33(40)48)14-8-9-17-39/h3-7, 10-13, 15-16, 18, 22-23, 29-32H, 8-9, 14, 17, 19-21, 39, 41H2, 1-2H3, (H2, 40, 48)(H, 42, 43)(H, 44, 49)(H, 45, 50)(H, 46, 51)(H, 47, 52)/t29-, 30+, 31+, 32-/m0/s1
InChIKeyNEHWBYHLYZGBNO-BVEPWEIPSA-N
Isomeric SMILES CC(C)(C(=O)N[C@@H](CC1=CN=CN1)C(=O)N[C@H](CC2=CC3=CC=CC=C3C=C2)C(=O)N[C@H](CC4=CC=CC=C4)C(=O)N[C@@H](CCCCN)C(=O)N)N
Canonical SMILES CC(C)(C(=O)NC(CC1=CN=CN1)C(=O)NC(CC2=CC3=CC=CC=C3C=C2)C(=O)NC(CC4=CC=CC=C4)C(=O)NC(CCCCN)C(=O)N)N
IUPAC Name (2S)-6-amino-2-[[(2R)-2-[[(2R)-2-[[(2S)-2-[(2-amino-2-methylpropanoyl)amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-3-naphthalen-2-ylpropanoyl]amino]-3-phenylpropanoyl]amino]hexanamide

Description

Ipamorelin Peptide: Enhance Your Research on Energy and Well-Being

NuScience Peptides sells research products only, they are not for human consumption.

Embark on a revitalized research journey with Ipamorelin Peptide. Amplify natural growth hormone production for in-depth studies on enhanced muscle growth, improved fat metabolism, and increased energy levels.

Ipamorelin Peptide is a synthetic 5 amino acid sequence developed as a small molecule, chemically stabilized analogy to the naturally occurring protein ghrelin1. Ipamorelin is a member of a classification of agents called growth hormone (GH) secretagogues that were collectively developed in an effort to artificially stimulate the release of GH2.

Ipamorelin is known to bind with the GH secretagogue receptor (ghrelin receptor) directly3, stimulating potent GH secretion in animal test subjects. Unlike its native analogy, ghrelin, Ipamorelin is a non-lipogenic peptide and suppresses somatostatin-induced regulation of GH production4.

The promotion of improved strength, increased muscle mass to body fat ratio, and the encouragement of good joint and connective tissue health has been observed in animal trials where high levels of GH release has been induced5. Ipamorelin, specifically, has been shown to also have a positive effect on bone growth in rats6.

Ipamorelin Peptide Side Effects

  • Mild Discomfort: Headaches or dizziness.
  • Injection Site Reactions: Redness, swelling, or irritation.
  • Nausea: Some may experience mild nausea.
  • Hunger Levels: Can influence appetite.

Ipamorelin Benefits:

  • Enhanced Growth Hormone Stimulation: Supports muscle growth.
  • Improved Muscle Mass: Increases lean muscle.
  • Fat Metabolism: Aids in fat reduction.
  • Joint Support: Enhances joint health.
  • Better Sleep: Positively impacts sleep quality.

What are the safety considerations and handling protocols for ipamorelin peptide in the lab?

Answer: When handling ipamorelin in a lab setting, it is crucial to follow appropriate safety protocols to ensure both researcher safety and the integrity of the compound:

  • Storage: Store ipamorelin lyophilized powder at -20°C and reconstituted solutions at 4°C for short-term use or -20°C for long-term storage.
  • Handling: Use personal protective equipment (PPE) including gloves, lab coat, and safety glasses. Avoid inhalation, ingestion, and contact with skin and eyes.
  • Disposal: Dispose of any unused ipamorelin peptide and related waste materials in accordance with institutional and governmental regulations.

Product Comparison

Similar to other agents of GH release, Ipamorelin Peptide acts on the anterior pituitary gland1. Ipamorelin’s mechanism of action is very similar to GHRP-2, being a ‘true’ GH secretagogue, reflecting its ability to stimulate the natural, body-mediated production of GH rather than introducing exogenous, synthetic agents to a physiological system.

Like GHRP-6 and GHRP-2, Ipamorelin Peptide acts synergistically with growth hormone-releasing hormone (GHRH) or any of its analogies, like Sermorelin or CJC-1295, to achieve a very potent release of GH7. In light of this observation, it has been possible for researchers to administrate GHRH’s or GHRH analogies with Ipamorelin concurrently in order to achieve an additive positive effect on GH release.

Unlike GHRP-6 and GHRP-2, which are known to release prolactin and cortisol along with GH, Ipamorelin Peptide is specific in its release of GH through a broad spectrum of doses1.

NuScience Peptides sells research products only, they are not for human consumption.

Synonyms:

Ipamorelin Acetate, IPAM, NNC-26-0161


Peer-Reviewed Sources:

  1. Raun, K., Hansen, B. S., Johansen, N. L., Thogersen, H., Madsen, K., Ankersen, M., & Andersen, P. H. (1998). Ipamorelin, the first selective growth hormone secretagogue. European Journal of Endocrinology, 139(5), 552-561.
  2. Casanueva, F. F., & Dieguez, C. (1999). Growth hormone secretagogues: physiological role and clinical utility. Trends in Endocrinology & Metabolism,10(1), 30-38.
  3. Holst, B., Cygankiewicz, A., Jensen, T. H., Ankersen, M., & Schwartz, T. W. (2003). High constitutive signaling of the ghrelin receptor—identification of a potent inverse agonist. Molecular Endocrinology, 17(11), 2201-2210.
  4. Jiménez Reina, L., Cañete, R., De La Torre, M. J., & Bernal, G. (2002). Influence of chronic treatment with the growth hormone secretagogue Ipamorelin, in young female rats somatotroph response in vitro.
  5. Jenkins, P. J. (1999). Growth hormone and exercise. Clinical endocrinology, 50(6), 683-689.
  6. Johansen, P. B., Nowak, J., Skjærbæk, C., Flyvbjerg, A., Andreassen, T. T., Wilken, M., & Ørskov, H. (1999). Ipamorelin, a new growth-hormone-releasing peptide, induces longitudinal bone growth in rats. Growth Hormone & IGF Research, 9(2), 106-113.
  7. Gobburu, J. V., Agersø, H., Jusko, W. J., & Ynddal, L. (1999). Pharmacokinetic-pharmacodynamic modeling of ipamorelin, a growth hormone releasing peptide, in human volunteers. Pharmaceutical research, 16(9), 1412-1416.
  8. Granado, M., Priego, T., Martín, A. I., Villanua, M. A., & López-Calderón, A. (2005). Anti-inflammatory effect of the ghrelin agonist growth hormone-releasing peptide-2 (GHRP-2) in arthritic rats. American Journal of Physiology-Endocrinology and Metabolism, 288(3), E486-E492.

ALL LITERATURE, INFORMATION, AND DATA, PROVIDED ON THIS WEBSITE ARE FOR INFORMATIONAL AND EDUCATIONAL PURPOSES ONLY.

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