Research Use Only: All products are supplied exclusively for laboratory, research, and analytical use. They are not intended for human or veterinary use.
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Snap-8 – 10mg

Original price was: $39.99.Current price is: $29.99.

10 mg per vial

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Properties

Molecular Formula
Molecular Weight 1075.2 g/mol
Monoisotopic Mass 1074.48764138 Da
Polar Area 585 Ų
Complexity2070
XLogP -7.7
Heavy Atom Count 74
Hydrogen Bond Donor Count 17
Hydrogen Bond Acceptor Count 19
Rotatable Bond Count 38
Physical Appearance Fine White Lyophilized Powder
Stability
PubChem LCSS

Identifiers

CID86080331
CAS
InChIInChI=1S/C41H70N16O16S/c1-19(33(67)57-27(32(43)66)18-31(64)65)50-34(68)21(6-4-15-48-40(44)45)52-35(69)22(7-5-16-49-41(46)47)53-37(71)24(8-11-28(42)59)54-39(73)26(14-17-74-3)56-38(72)25(10-13-30(62)63)55-36(70)23(51-20(2)58)9-12-29(60)61/h19,21-27H,4-18H2,1-3H3,(H2,42,59)(H2,43,66)(H,50,68)(H,51,58)(H,52,69)(H,53,71)(H,54,73)(H,55,70)(H,56,72)(H,57,67)(H,60,61)(H,62,63)(H,64,65)(H4,44,45,48)(H4,46,47,49)
InChIKeyKMACPCJUCHVVGP-UHFFFAOYSA-N
Isomeric SMILES CC(C(=O)NC(CC(=O)O)C(=O)N)NC(=O)C(CCCN=C(N)N)NC(=O)C(CCCN=C(N)N)NC(=O)C(CCC(=O)N)NC(=O)C(CCSC)NC(=O)C(CCC(=O)O)NC(=O)C(CCC(=O)O)NC(=O)C
Canonical SMILES
IUPAC Name 4-acetamido-5-[[1-[[1-[[5-amino-1-[[1-[[1-[[1-[(1-amino-3-carboxy-1-oxopropan-2-yl)amino]-1-oxopropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-1,5-dioxopentan-2-yl]amino]-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-carboxy-1-oxobutan-2-yl]amino]-5-oxopentanoic acid

Description

Snap-8

This product is not intended for weight loss, human consumption, or veterinary use. It is sold for research purposes only. Please handle with care and follow all safety guidelines for the specific chemicals involved.

SNAP-8, also known as acetyl octapeptide-3, is a synthetic snap 8 peptide developed as a topical alternative to botulinum toxin (BoNT) for reducing dynamic facial wrinkles. It functions by inhibiting the SNARE complex, thereby modulating neurotransmitter release and attenuating muscle contractions that lead to expression lines. (ResearchGate)

In vitro studies have demonstrated that the snap 8 peptide can decrease the depth of wrinkles by up to 63% by reducing muscle contractions. This effect is attributed to its ability to inhibit the formation of the SNARE complex, which is essential for neurotransmitter release at the neuromuscular junction. By preventing this complex’s assembly, SNAP-8 reduces muscle activity, leading to a smoother skin appearance. (HubMedEd)

Clinical evaluations have further supported SNAP-8’s efficacy. A study assessing a serum containing SNAP-8 reported a significant reduction in wrinkle depth after four weeks of application, with participants exhibiting improved skin smoothness and elasticity. These findings are often referenced by individuals looking to buy snap-8 peptide for advanced cosmetic research, as the data highlights its performance potential. (PMC)

Analytical methods have been developed to quantify SNAP-8 in cosmetic formulations, ensuring product consistency and efficacy. Liquid chromatography-tandem mass spectrometry (LC-MS/MS) techniques have been employed to detect and measure SNAP-8 concentrations in various delivery systems, including microneedle patches. These methods provide accurate quantification, facilitating quality control in product development. (SpringerOpen)

The increasing popularity of SNAP-8 in the cosmetic industry is reflected in consumer interest and market trends. A longitudinal analysis of internet search data indicated a growing public interest in acetyl hexapeptide-8, the trade name for SNAP-8, over the past decade—particularly among users wanting to know where to buy SNAP-8 peptide as non-invasive, cost-effective alternatives to BoNT continue to scale. (PMC)

In summary, SNAP-8 is a promising peptide for cosmetic applications, offering a non-invasive approach to reducing facial wrinkles. Its mechanism of action, clinical efficacy, and growing consumer interest underscore its potential as a valuable ingredient in anti-aging skincare products.(ResearchGate)

Works Cited

  1. Jung, Jae Hoon, et al. “Method development for acetyl octapeptide-3 analysis by liquid chromatography-tandem mass spectrometry.” Journal of Analytical Science and Technology, vol. 11, no. 1, 2020, pp. 1-9. https://jast-journal.springeropen.com/articles/10.1186/s40543-020-00232-8(SpringerOpen)
  2. “Public Interest in Acetyl Hexapeptide-8: Longitudinal Analysis.” PubMed Central, National Institutes of Health, https://pmc.ncbi.nlm.nih.gov/articles/PMC10915729/(PMC)
  3. “Investigating the effects of Argireline in a skin serum containing acetyl hexapeptide-8.” PubMed Central, National Institutes of Health, https://pmc.ncbi.nlm.nih.gov/articles/PMC10665711/(PMC)
  4. “Non-Invasive Peptides as the Future of Botox Alternatives.” MDPI, https://www.mdpi.com/2079-9284/11/4/118(MDPI)

ALL LITERATURE, INFORMATION, AND DATA, PROVIDED ON THIS WEBSITE ARE FOR INFORMATIONAL AND EDUCATIONAL PURPOSES ONLY.

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Frequently Asked Questions

Everything you need to know about SNAP-8 research peptide

1What does SNAP-8 do?
SNAP-8 works by relaxing facial muscles without completely paralyzing them. In research studies, it has been shown to reduce wrinkle depth by up to 63% after 28 days of use. It targets dynamic wrinkles caused by repetitive facial expressions, particularly around the eyes (crow’s feet) and forehead.
2Where to buy SNAP-8 peptide?
SNAP-8 peptide can be purchased directly from NuScience Peptides. It is supplied for research use only, with batch purity documentation, and is not intended for human consumption.
3How much does SNAP-8 cost?
SNAP-8 peptide starts at $49 for 5mg vials. We offer volume discounts: Buy 3 vials and save 10%, buy 5+ and save 15%. Current promotion: Use code SNAP10 for 10% off your first order.
4How to use the SNAP-8 peptide?

For research purposes:

1. Reconstitute lyophilized SNAP-8 with bacteriostatic water or sterile saline
2. Use at 3-10% concentration in topical formulations
3. Apply to target areas twice daily
4. Store reconstituted solution at 2-8°C (refrigerator)
5. Use within 30 days after reconstitution.

Always follow your research protocol guidelines.

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