Research Use Only: All products are supplied exclusively for laboratory, research, and analytical use. They are not intended for human or veterinary use.

Tesamorelin Research Peptide for Sale

$69.99

10 mg per vial

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Properties

Molecular Formula

C221H366N72O67S

Molecular Weight 5136
Monoisotopic Mass 5132.7166406
Polar Area 2360
Complexity12800
XLogP -23.3
Heavy Atom Count 361
Hydrogen Bond Donor Count 83
Hydrogen Bond Acceptor Count 76
Rotatable Bond Count 187
Physical Appearance Fine White Lyophilized Powder
StabilityLyophilized protein is to be stored at -20°C. It is recommended to aliquot the reconstituted (dissolved) protein into several discrete vials in order to avoid repeated freezing and thawing. Reconstituted protein can be stored at 4°C
PubChem LCSS

Tesamorelin Laboratory Chemical Safety Summary

Identifiers

CID16137828
CAS218949-48-5
InChI InChI=1S/C221H366N72O67S/c1-25-28-30-53-163(308)260-145(92-120-54-58-122(299)59-55-120)198(343)255-116(21)179(324)276-150(96-169(316)317)199(344)256-117(22)180(325)291-172(111(16)26-2)214(359)284-147(91-119-43-31-29-32-44-119)206(351)293-174(118(23)298)215(360)285-149(95-162(230)307)205(350)289-155(104-297)210(355)280-146(93-121-56-60-123(300)61-57-121)203(348)267-130(51-41-83-248-220(240)241)186(331)266-126(46-34-36-78-223)197(342)290-171(110(14)15)212(357)283-141(87-106(6)7)183(328)252-100-166(311)258-133(63-70-157(225)302)190(335)278-144(90-109(12)13)202(347)288-152(101-294)208(353)257-115(20)178(323)262-128(49-39-81-246-218(236)237)185(330)265-125(45-33-35-77-222)189(334)277-143(89-108(10)11)201(346)279-142(88-107(8)9)200(345)272-137(66-73-160(228)305)195(340)282-151(97-170(318)319)207(352)292-173(112(17)27-3)213(358)274-139(76-85-361-24)196(341)287-153(102-295)209(354)268-131(52-42-84-249-221(242)243)187(332)270-135(64-71-158(226)303)192(337)269-132(62-69-156(224)301)182(327)251-99-165(310)259-134(67-74-167(312)313)191(336)286-154(103-296)211(356)281-148(94-161(229)306)204(349)273-136(65-72-159(227)304)193(338)271-138(68-75-168(314)315)194(339)264-124(47-37-79-244-216(232)233)181(326)250-98-164(309)253-113(18)176(321)261-127(48-38-80-245-217(234)235)184(329)254-114(19)177(322)263-129(50-40-82-247-219(238)239)188(333)275-140(175(231)320)86-105(4)5/h28-32, 43-44, 54-61, 105-118, 124-155, 171-174, 294-300H, 25-27, 33-42, 45-53, 62-104, 222-223H2, 1-24H3, (H2, 224, 301)(H2, 225, 302)(H2, 226, 303)(H2, 227, 304)(H2, 228, 305)(H2, 229, 306)(H2, 230, 307)(H2, 231, 320)(H, 250, 326)(H, 251, 327)(H, 252, 328)(H, 253, 309)(H, 254, 329)(H, 255, 343)(H, 256, 344)(H, 257, 353)(H, 258, 311)(H, 259, 310)(H, 260, 308)(H, 261, 321)(H, 262, 323)(H, 263, 322)(H, 264, 339)(H, 265, 330)(H, 266, 331)(H, 267, 348)(H, 268, 354)(H, 269, 337)(H, 270, 332)(H, 271, 338)(H, 272, 345)(H, 273, 349)(H, 274, 358)(H, 275, 333)(H, 276, 324)(H, 277, 334)(H, 278, 335)(H, 279, 346)(H, 280, 355)(H, 281, 356)(H, 282, 340)(H, 283, 357)(H, 284, 359)(H, 285, 360)(H, 286, 336)(H, 287, 341)(H, 288, 347)(H, 289, 350)(H, 290, 342)(H, 291, 325)(H, 292, 352)(H, 293, 351)(H, 312, 313)(H, 314, 315)(H, 316, 317)(H, 318, 319)(H4, 232, 233, 244)(H4, 234, 235, 245)(H4, 236, 237, 246)(H4, 238, 239, 247)(H4, 240, 241, 248)(H4, 242, 243, 249)/b30-28+/t111-, 112-, 113-, 114-, 115-, 116-, 117-, 118+, 124-, 125-, 126-, 127-, 128-, 129-, 130-, 131-, 132-, 133-, 134-, 135-, 136-, 137-, 138-, 139-, 140-, 141-, 142-, 143-, 144-, 145-, 146-, 147-, 148-, 149-, 150-, 151-, 152-, 153-, 154-, 155-, 171-, 172-, 173-, 174-/m0/s1
InChIKeyQBEPNUQJQWDYKU-BMGKTWPMSA-N
Isomeric SMILES CC/C=C/CC(=O)N[C@@H](CC1=CC=C(C=C1)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC2=CC=CC=C2)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC3=CC=C(C=C3)O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCC(=O)N)C(=O)NCC(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC(C)C)C(=O)N
Canonical SMILES CCC=CCC(=O)NC(CC1=CC=C(C=C1)O)C(=O)NC(C)C(=O)NC(CC(=O)O)C(=O)NC(C)C(=O)NC(C(C)CC)C(=O)NC(CC2=CC=CC=C2)C(=O)NC(C(C)O)C(=O)NC(CC(=O)N)C(=O)NC(CO)C(=O)NC(CC3=CC=C(C=C3)O)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCCCN)C(=O)NC(C(C)C)C(=O)NC(CC(C)C)C(=O)NCC(=O)NC(CCC(=O)N)C(=O)NC(CC(C)C)C(=O)NC(CO)C(=O)NC(C)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCCCN)C(=O)NC(CC(C)C)C(=O)NC(CC(C)C)C(=O)NC(CCC(=O)N)C(=O)NC(CC(=O)O)C(=O)NC(C(C)CC)C(=O)NC(CCSC)C(=O)NC(CO)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCC(=O)N)C(=O)NC(CCC(=O)N)C(=O)NCC(=O)NC(CCC(=O)O)C(=O)NC(CO)C(=O)NC(CC(=O)N)C(=O)NC(CCC(=O)N)C(=O)NC(CCC(=O)O)C(=O)NC(CCCNC(=N)N)C(=O)NCC(=O)NC(C)C(=O)NC(CCCNC(=N)N)C(=O)NC(C)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC(C)C)C(=O)N
IUPAC Name (4S)-4-[[2-[[(2S)-5-amino-2-[[(2S)-5-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S, 3S)-2-[[(2S)-2-[[(2S)-5-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-5-amino-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-4-amino-2-[[(2S, 3R)-2-[[(2S)-2-[[(2S, 3S)-2-[[(2S)-2-[[(2S)-3-carboxy-2-[[(2S)-2-[[(2S)-2-[[(E)-hex-3-enoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]propanoyl]amino]propanoyl]amino]-3-methylpentanoyl]amino]-3-phenylpropanoyl]amino]-3-hydroxybutanoyl]amino]-4-oxobutanoyl]amino]-3-hydroxypropanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-5-carbamimidamidopentanoyl]amino]hexanoyl]amino]-3-methylbutanoyl]amino]-4-methylpentanoyl]amino]acetyl]amino]-5-oxopentanoyl]amino]-4-methylpentanoyl]amino]-3-hydroxypropanoyl]amino]propanoyl]amino]-5-carbamimidamidopentanoyl]amino]hexanoyl]amino]-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-5-oxopentanoyl]amino]-3-carboxypropanoyl]amino]-3-methylpentanoyl]amino]-4-methylsulfanylbutanoyl]amino]-3-hydroxypropanoyl]amino]-5-carbamimidamidopentanoyl]amino]-5-oxopentanoyl]amino]-5-oxopentanoyl]amino]acetyl]amino]-5-[[(2S)-1-[[(2S)-4-amino-1-[[(2S)-5-amino-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-1-oxopropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-1-oxopropan-2-yl]amino]-2-oxoethyl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-4-carboxy-1-oxobutan-2-yl]amino]-1, 5-dioxopentan-2-yl]amino]-1, 4-dioxobutan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-5-oxopentanoic acid

Description

Tesamorelin

Tesamorelin research peptide for sale at 99%+ purity, verified by HPLC and mass spectrometry, with a batch-specific Certificate of Analysis available before you order. Supplied by NuScience Peptides from the USA for laboratory and analytical research use only.

What Is Tesamorelin?

Tesamorelin is a stabilized synthetic analog of growth hormone-releasing hormone (GHRH), a 44-amino-acid peptide with an added trans-3-hexenoyl group that improves stability over native GHRH. In preclinical research it is used to study GHRH-receptor activity and the somatotroph signaling that governs growth hormone secretion, which is why it appears in metabolic and endocrine research models.

Tesamorelin Purity and COA Verification

Every batch is independently third-party tested in the USA and verified by HPLC and mass spectrometry to confirm identity and 99%+ purity, with a batch-specific Certificate of Analysis published for each lot. To compare specifications across the catalog, browse all research peptides.

Buy Tesamorelin Research Peptide Online

NuScience Peptides supplies tesamorelin in research-grade vials. Orders placed before 12 PM EST ship the same day from the USA, with free shipping over $200. For the full range of research peptides for sale, check the Certificate of Analysis for any batch before you order.

This product is not intended for weight loss, human consumption, or veterinary use. It is sold for research purposes only. Please handle with care and follow all safety guidelines for the specific chemicals involved.

Tesamorelin MUST be reconstituted with 3ml STERILE water (Not BAC),

and

the peptide as well as water must be kept at room temperature prior to reconstitution.

Tesamorelin: GH Secretion and Metabolic Effects in Rat Models

Administering tesamorelin to rats has been shown to enhance endogenous GH pulsatility, leading to increased insulin-like growth factor I (IGF-I) levels without adversely affecting insulin sensitivity. This suggests its utility in studying metabolic regulation and endocrine function in animal models.

Tesamorelin Peptide: Muscle Composition and Adipose Tissue Research

Beyond metabolic effects, tesamorelin has demonstrated the ability to reduce muscle fat and increase muscle area in clinical studies, indicating its potential for investigating muscle composition and function in rats. Such findings are particularly relevant for exploring interventions in muscle-wasting conditions.

Additionally, tesamorelin has been observed to improve fat quality independent of changes in fat quantity, highlighting its role in adipose tissue research. This property makes it a valuable tool for studying the qualitative aspects of fat tissue and their implications on overall metabolic health.

Furthermore, research indicates that tesamorelin may enhance cognitive function, including improvements in executive function and verbal memory. These cognitive benefits open avenues for exploring its effects on brain function and neuroendocrine interactions in rodent models.

Tesamorelin: Research Summary and Preclinical Outlook

In summary, tesamorelin’s multifaceted effects on GH secretion, muscle composition, adipose tissue quality, and cognitive function make it a promising compound for comprehensive rat studies aimed at understanding metabolic and neuroendocrine dynamics.

Buy tesamorelin from NuScience Peptides to advance your growth hormone research. Explore related GHRH compounds including the Tesamorelin/Ipamorelin blend for synergistic GH-axis studies and Sermorelin for comparative GHRH analogue research. Use our Peptide Calculator to determine reconstitution volumes.

References:

  1. Stanley, T. L., Chen, C. Y., Branch, K. L., Makimura, H., & Grinspoon, S. K. (2011). Effects of a growth hormone-releasing hormone analog on endogenous GH pulsatility and insulin sensitivity in healthy men. The Journal of Clinical Endocrinology & Metabolism, 96(1), 150–158. https://pubmed.ncbi.nlm.nih.gov/20943777/
  2. Adrian, S., Scherzinger, A., Sanyal, A., Lake, J. E., Falutz, J., Dubé, M. P., … & Erlandson, K. M. (2019). The Growth Hormone Releasing Hormone Analogue, Tesamorelin, Decreases Muscle Fat and Increases Muscle Area in Adults with HIV. The Journal of Frailty & Aging, 8(3), 154–159. https://pmc.ncbi.nlm.nih.gov/articles/PMC6766405/
  3. Lake, J. E., Moser, C., Johnston, L., Magyar, C., Nelson, S. D., Erlandson, K. M., … & Stanley, T. L. (2021). Tesamorelin Improves Fat Quality Independent of Changes in Fat Quantity. The Journal of Clinical Endocrinology & Metabolism, 106(7), e2710–e2718. https://pmc.ncbi.nlm.nih.gov/articles/PMC8243807/
  4. Baker, L. D., Barsness, S. M., Borson, S., Merriam, G. R., Friedman, S. D., Craft, S., & Peskind, E. R. (2011). O3‐07‐08: Tesamorelin, a growth hormone‐releasing hormone analogue, improves cognitive function in MCI and healthy aging: Results of a randomized controlled trial. Alzheimer’s & Dementia, 7(4), S608. https://alz-journals.onlinelibrary.wiley.com/doi/full/10.1016/j.jalz.2011.05.1439
  5. Clemmons, D. R., Miller, S., & Mamputu, J. C. (2017). Safety and metabolic effects of tesamorelin, a growth hormone-releasing factor analogue, in patients with type 2 diabetes: A randomized, placebo-controlled trial. PLoS ONE, 12(6), e0179538. https://pmc.ncbi.nlm.nih.gov/articles/PMC5472315/

NuScience Peptides has tesamorelin peptide for sale in both 10mg and 20mg research-grade formats – strictly for laboratory use, not for human consumption.

ALL LITERATURE, INFORMATION, AND DATA, PROVIDED ON THIS WEBSITE ARE FOR INFORMATIONAL AND EDUCATIONAL PURPOSES ONLY.

NuScience Peptides third-party tested research peptides, USA shipping

Accurate research is our number one priority.

Same Day Shipping

Enjoy the convenience of receiving your order swiftly. We offer same-day shipping on all orders of in-stock items placed before 12:00 pm EST.

Dedicated Service

Our dedicated team is always at your service, Ready to assist you with any customer service requests you may have. We prioritize your satisfaction and aim to provide a seamless experience.

Free Shipping

To enhance your shopping experience, We offer free shipping on all orders totaling $200 or more. Rest assured, we've got you covered!

Purist Quality

We take pride in ensuring the utmost purity of our products. Every item we offer undergoes rigorous lab testing and is certified for the highest possible purity.

Tesamorelin injection is used to decrease the amount of extra fat in the stomach area in adults with human immunodeficiency virus (HIV)

Frequently Asked Questions

1What is the difference between tesamorelin 10mg and 20mg?
NuScience Peptides offers tesamorelin in both 10mg and 20mg research-grade vials. The 20mg format provides a higher concentration per vial, suitable for longer research protocols or studies requiring larger volumes. Both formats are 99% pure and include a Certificate of Analysis.
2How does tesamorelin affect muscle composition in research?
In preclinical and clinical studies, tesamorelin has demonstrated the ability to reduce muscle fat and increase muscle area. These findings are particularly relevant for exploring interventions in muscle-wasting conditions and understanding the relationship between GH secretion and body composition.
3What is tesamorelin used for in preclinical research?
Tesamorelin is studied for its effects on GH secretion, metabolic regulation, visceral adipose tissue reduction, muscle composition, adipose tissue quality, and cognitive function in animal models. Its multifaceted effects make it a promising compound for comprehensive rat studies on metabolic and neuroendocrine dynamics.
4Where is tesamorelin peptide for sale?
Tesamorelin peptide is for sale at NuScience Peptides in 10mg and 20mg research-grade vials. All products are documented with complete lab test results, with same-day shipping on in-stock orders before 12:00 PM EST and free shipping over $200.
5What does tesamorelin do in research?
As a GHRH analog, tesamorelin is used in laboratory models to study stimulation of the GHRH receptor and downstream growth-hormone secretion pathways.
6What is tesamorelin used for in laboratory study?
It is a reference compound for GHRH-receptor and somatotroph-pathway research. It is supplied strictly for in vitro and analytical use, not for human or animal use.
7How is tesamorelin different from sermorelin?
Both are GHRH analogs, but tesamorelin carries a stabilizing modification that extends its stability, which researchers weigh when selecting a GHRH reference peptide.
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